一、照片
二、姓名:张婷
三、性别:女
四、出生年月:1991.04
五、学位、学历:博士研究生
六、职称:副教授
七、学术兼职情况:无
八、基本情况
2014-06,兰州大学生命科学学院毕业,获得理学学士学位;2019-06,兰州大学基础yl34511线路中心生物化学系毕业,获得理学博士学位;2019-09入职yl34511线路中心,担任基础医学系讲师;2020-07聘任为yl34511线路中心基础医学系副教授。
(1)主要研究内容:
1、非酒精性脂肪肝的发病机制;
2、中草药成分羟基积雪草苷在烧伤痛中的生理作用及其机制研究。
(2)目前承担科研项目:
1. miRNA 靶向调控 PPARG 的表达在非酒精性脂肪肝病中影响脂质积累的研究(ZZZC202129),校级项目,2022/1-2023/12,在研,主持。
2. 嘌呤受体P2Y通过TRPV1信号通路调节烧伤痛痛觉敏感形成的研究(校20210016),高层次人才科研启动项目,2021/1-2023/7,在研,主持。
(3)学术论文发表情况:
1. Ting Zhang, Run Zhang, Biao Xu, Mengna Zhang, Qinqin Zhang, Ning Li, Yu Qiu, Dan Chen, Kangtai Xu, Jian Xiao, Nan Zhang, Quan Fang. Spinal endomorphins attenuate burn-injury pain in male mice by inhibiting p38 MAPK signaling pathway through the mu-opioid receptor. Eur J Pharmacol. 2021 Jul 15;903:174139.
2. Zhang T, Han ZL, Wang ZL, Zhao WD, Zhang R, Wang P, Xu B, Zhang MN, Li N, Fang Q, Wang R. Discovery of two novel branched peptidomimetics containing endomorphin-2 and RF9 pharmacophores: Synthesis and neuropharmacological evaluation. Bioorganic & Medicinal Chemistry, 2019, 27: 630-643.
3. Zhang T, Zhang N, Zhang R, Zhao WD, Chen Y, Wang ZL, Xu B, Zhang MN, Shi XR, Zhang QQ, Guo YY, Xiao J, Chen D, Fang Q. Preemptive intrathecal administration of endomorphins relieves inflammatory pain in male mice via inhibition of p38 MAPK signaling and regulation of inflammatory cytokines. Journal of Neuroinflammation, 2018, 15: 320.
4. Zhang T, Zhao WD, Zhang MN, Xu B, Shi XR, Zhang QQ, Guo YY, Xiao J, Chen D, Zheng T, Fang Q. Analgesic activities of the mixed opioid and NPFF receptors agonist DN-9 in a mouse model of formalin-induced orofacial inflammatory pain. Peptides, 2018, 110: 30-39.
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